Causes Of Coeliac Disease

Coeliac disease is thought to have a strong genetic component. The onset of Coeliac disease has been associated with genes on Chromosome 6 called Human Leukocyte Antigens (HLA) class II. HLA II genes affect an individual's susceptibility to disease by mediating the interactions between cells of the immune system. An individual may be genetically predisposed to Coeliac disease, but the actual mechanism of onset is not fully understood. Emotional stress, physical trauma, viral infection, pregnancy, and surgery are some of the factors implicated in the onset of Coeliac disease.